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DISEASE INFORMATION

Strongyloidiasis

We are collaborating on clinical trials for a new treatment for this sometimes fatal common infection

OVERVIEW

What is strongyloidiasis?

Strongyloidiasis is a soil-transmitted helminth infection caused by strongyloides stercoralis. The WHO estimates that up to 100 million people, particularly children, are infected with this parasitic worm. The causative worm has a different lifecycle from other soil-transmitted helminths and infection can be fatal.

THE STATS

Why are we working to treat this disease?

100m

Up to 100 million people, particularly children, are infected

0

0 public health strategies for controlling this disease are active at the global level

Source:

World Health Organization. Ending the neglect to attain the Sustainable Development Goals: A road map for neglected tropical diseases 2021–2030 [Internet]. Geneva: World Health Organization; 2020. Available from: https://www.who.int/ teams/control-of-neglected-tropical-diseases/ending-ntds-together-towards-2030

World Health Organization. WHO Strongyloidiasis fact sheet [Internet]. WHO. World Health Organization; [cited 2021 Mar 25]. Available from: http://www.who.int/intestinal_worms/epidemiology/strongyloidiasis/en/

Children are particularly vulnerable to this infection

INFOGRAPHIC

Transmission Stages of Onchocerca volvulus

WHAT we're DOING

Strongyloidiasis

Treatment options are limited, with ivermectin, an anti-parasitic, being the medicine of choice, while other anthelmintic medicines such as albendazole and mebendazole, which limit the parasite’s absorption of sugar, lack sufficient efficacy as a single dose.  

MDGH is collaborating in clinical trials of moxidectin as a treatment for strongyloidiasis in Cambodia and Laos led by the Swiss Tropical and Public Health Institute, Switzerland.

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Take a look at the research and development work

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An infectious skin condition affecting more than 200 million people at any one time.

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A painful and debilitating disease of the lymph system affecting over 50 million people at any one time.

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A soil-transmitted infection affecting up to 100 million people, particularly children.

Strongyloidiasis

A chronic infectious disease which may cause skin lesions and nerve damage found in 127 countries.

Leprosy

Among the most common of all infections with an estimated 1.5 billion people infected worldwide.

Soil-transmitted helminth infections